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PET radiotracer
11C-UCB-J
Другие языки:

    11C-UCB-J

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    11C-UCB-J
    11C-UCB-J.svg
    Names
    Preferred IUPAC name
    (4R)-1-{[3-(11C)Methylpyridin-4-yl]methyl}-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one
    Other names
    [11C]UCB-J; 11C-UCB-J; [11C]UCB-J
    Identifiers
    3D model (JSmol)
    PubChem CID
    UNII
    • InChI=1S/C17H15F3N2O/c1-10-7-21-3-2-11(10)8-22-9-13(6-16(22)23)12-4-14(18)17(20)15(19)5-12/h2-5,7,13H,6,8-9H2,1H3/t13-/m0/s1/i1-1
      Key: RFSDYRVOGWHOFT-XOTOJZTHSA-N
    • [11CH3]C1=CN=CC=C1CN1C[C@H](CC1=O)C1=CC(F)=C(F)C(F)=C1
    Properties
    C17H15F3N2O
    Molar mass 320.315 g·mol−1
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    11C-UCB-J is a PET tracer for imaging the synaptic vesicle glycoprotein 2A in the human brain.

    It is used to study the brain changes associated with several diseases including Alzheimer's disease,schizophrenia, and depression.


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