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Human drug metabolites
19-Noretiocholanolone
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    19-Noretiocholanolone

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    19-Noretiocholanolone
    19-Noretiocholanolone.svg
    Clinical data
    Other names Noretiocholanolone; 5β-Estran-3α-ol-17-one; 3α-Hydroxy-5β-estran-17-one
    Identifiers
    • (3R,5R,8R,9R,10S,13S,14S)-3-Hydroxy-13-methyl-2,3,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-1H-cyclopenta[a]phenanthren-17-one
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C18H28O2
    Molar mass 276.420 g·mol−1
    3D model (JSmol)
    • C[C@]12CC[C@@H]3[C@H]4CC[C@H](C[C@H]4CC[C@H]3[C@@H]1CCC2=O)O
    • InChI=1S/C18H28O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h11-16,19H,2-10H2,1H3/t11-,12-,13+,14-,15-,16+,18+/m1/s1
    • Key:UOUIARGWRPHDBX-DHMVHTBWSA-N

    19-Noretiocholanolone, also known as 5β-estran-3α-ol-17-one, is a metabolite of nandrolone (19-nortestosterone) and bolandione (19-norandrostenedione) that is formed by 5α-reductase. It is on the list of substances prohibited by the World Anti-Doping Agency since it is a detectable metabolite of nandrolone, an anabolic-androgenic steroid (AAS).

    Traces of 19-noretiocholanolone may be naturally present in human urine. Consumption of boar meat, liver, kidneys and heart have been found to increase urinary 19-noretiocholanolone output.

    See also


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