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Pharmacology stubs
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a
Другие языки:

    2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a

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    2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a
    Photochlor.png
    Names
    Other names
    Photochlor
    Identifiers
    3D model (JSmol)
    Abbreviations HPPH
    ChemSpider
    PubChem CID
    UNII
    • InChI=1S/C39H48N4O4/c1-8-10-11-12-15-47-24(7)36-22(5)30-17-29-21(4)26(13-14-35(45)46)38(42-29)27-16-34(44)37-23(6)31(43-39(27)37)18-32-25(9-2)20(3)28(40-32)19-33(36)41-30/h17-19,21,24,26,40-41H,8-16H2,1-7H3,(H,45,46)/b28-19-,29-17-,30-17-,31-18-,32-18-,33-19-,38-27-/t21-,24?,26-/m0/s1 checkY
      Key: ODJVLHDVEGAIAW-NMWXTPPCSA-N checkY
    • InChI=1/C39H48N4O4/c1-8-10-11-12-15-47-24(7)36-22(5)30-17-29-21(4)26(13-14-35(45)46)38(42-29)27-16-34(44)37-23(6)31(43-39(27)37)18-32-25(9-2)20(3)28(40-32)19-33(36)41-30/h17-19,21,24,26,40-41H,8-16H2,1-7H3,(H,45,46)/b28-19-,29-17-,30-17-,31-18-,32-18-,33-19-,38-27-/t21-,24?,26-/m0/s1
      Key: ODJVLHDVEGAIAW-NMWXTPPCBI
    • CCCCCCOC(C)C1=C2C=C3C(=C(C(=CC4=NC5=C(CC(=O)C5=C4C)C6=NC(=CC(=C1C)N2)[C@H]([C@@H]6CCC(=O)O)C)N3)CC)C
    Properties
    C39H48N4O4
    Molar mass 636.837 g·mol−1
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
    ☒N verify (what is checkY☒N ?)

    2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a (HPPH) is a photosensitiser chemical that is used in photodynamic therapy.

    It is being developed under the brand name Photochlor.

    Clinical trials

    A phase I/II clinical trial started in 1997 for esophageal cancer.

    A phase II trial for non-small cell lung cancer is due to run from 2007 to 2011.

    External links



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