2-Hydroxyisocaproic acid
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Preferred IUPAC name
2-Hydroxy-4-methylpentanoic acid | |
| Other names
2-Hydroxy-4-methylvaleric acid
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| Identifiers | |
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3D model (JSmol)
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| ChemSpider | |
| ECHA InfoCard | 100.007.147 |
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PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C6H12O3 | |
| Molar mass | 132.159 g·mol−1 |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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2-Hydroxyisocaproic acid (HICA or leucic acid) is a metabolite of the branched-chain amino acid leucine. It is commonly sold as a purported muscle building supplement. It also has fungicidal properties. HICA was shown to increase protein synthesis and muscle mass in rats who were recovering from a period of induced atrophy.
HICA is also produced by several protozoans it has been reported to show anti- inflammatory activities.