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2022–2023 United Kingdom group A streptococcus outbreak
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    2022–2023 United Kingdom group A streptococcus outbreak

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    2022–2023 United Kingdom Lancefield group A streptococcus outbreak
    Child with scarlet fever.jpg
    The tongue of a child showing the signs of scarlet fever caused by Lancefield group A streptococci
    Disease Group A streptococcal infection (iGAS)
    Scarlet fever
    Bacteria strain Group A streptococcus
    Location United Kingdom
    Date 12 September 2022 (2022-09-12) – present
    Confirmed cases iGAS: 2,965
    Scarlet fever: 54,394
    Deaths
    428
    Fatality rate 14.2% (iGAS)

    In late 2022, an ongoing disease outbreak caused by the bacterium Streptococcus pyogenes, a Lancefield group A streptococcus, began in the United Kingdom. It is often referred to as the Strep A outbreak in the media. These bacteria cause group A streptococcal infections (Strep A or iGAS) and scarlet fever. In the UK, 428 deaths from iGAS have been recorded, of which 54 were children, 45 in England, five in Wales, three in Scotland, and one in Northern Ireland.

    There were 2,965 notifications of iGAS recorded in England between 12 September 2022 and 16 April 2023. Notifications of scarlet fever have also seen a large increase, with 54,394 infections reported in England during the same period.

    Background

    Group A streptococcal infections are diseases, including scarlet fever, which are caused by the bacterium Streptococcus pyogenes, a Lancefield group A streptococcus (GAS). In 2007 it was estimated that GAS infections cause over 500,000 deaths per year. On very rare occasions, GAS enter the bloodstream and cause an illness called invasive group A strep (iGAS) which is very serious, particularly in older, younger and more vulnerable groups.

    In the United Kingdom, the UK Health Security Agency (UKHSA) has said that the last comparably high season was the 2017/18 season, where 355 deaths occurred from iGAS, 27 of which were children. During this season the UKHSA also received total of 30,768 reports of scarlet fever.

    Deaths

    So far, 428 deaths have been recorded within 7 days of an iGAS infection, 54 of which were children. The other reported deaths are people over the age of at least 15. Usually, only one or two children under the age of 10 die from GAS infections during a typical winter.

    The case fatality rate (CFR) for iGAS from 12 September to 16 April in England was 14.2%.

    Country Child deaths Adult deaths Total
     England 45 356 401
     Scotland 3 16 19
     Wales 5 - 5
    Northern Ireland 1 - 1
    United Kingdom Total 54 372 428
    As of 16 April 2023

    Cases

    The UK Health Security Agency (UKHSA) said that an average of 2,861 (range 479 to 5,051) of scarlet fever were recorded during the same period over the past 5 years.

    The following table shows the number of notifications of iGAS and scarlet fever published by data from the UKHSA from 12 September to 16 April.

    Country iGAS Scarlet fever Total
     England 2,965 54,394 49,262
     Scotland - - -
     Wales - - -
    Northern Ireland - - -
    United Kingdom Total 2,965 54,394 57,259
    As of 16 April 2023

    Response

    During a House of Commons debate on 7 December 2022, Prime Minister Rishi Sunak was accused of downplaying the outbreak after leader of the opposition Keir Starmer questioned him on his handling of the disease. Sunak stated that the infection 'has not become more lethal'.

    A survey of 626 parents' attitudes towards Strep A revealed a range of misinformation narratives, with 32% thinking that COVID-19 vaccines and flu vaccines were partly responsible for an increase in Strep A infections. Furthermore, 49% were unsure as to whether there is a link between nasal flu vaccines and Strep A. It also found that 28% were sceptical about Strep A, believing that it is a disguise being used to cover up something else. Increasing migration and refugee numbers were blamed by 33% of respondents for the increase in infections.


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