5-Fluoro-DMT

5-Fluoro-DMT

Identifiers
IUPAC name 2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine
CAS Number	22120-36-1 Y
PubChem CID	2762738
ChemSpider	2043436 Y
ChEMBL	ChEMBL1630729
CompTox Dashboard (EPA)	DTXSID30376407
Chemical and physical data
Formula	C12H15FN2
Molar mass	206.264 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)F
InChI InChI=1S/C12H15FN2/c1-15(2)6-5-9-8-14-12-4-3-10(13)7-11(9)12/h3-4,7-8,14H,5-6H2,1-2H3 Y Key:BXYDWQABVPBLBU-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

5-Fluoro-N,N-dimethyltryptamine (5-fluoro-DMT, 5F-DMT) is a tryptamine derivative related to compounds such as 5-bromo-DMT and 5-MeO-DMT. Fluorination of psychedelic tryptamines either reduces or has little effect on 5-HT_2A/C receptor affinity or intrinsic activity, although 6-fluoro-DET is inactive as a psychedelic despite acting as a 5-HT_2A agonist (cf. lisuride), while 4-fluoro-5-methoxy-DMT is a much stronger agonist at 5-HT_1A than 5-HT_2A.

See also

• 5-Fluoro-AMT
• 5-Fluoro-DET
• 5-Fluoro-MET
• 6-fluoro-AMT
• 6-Fluoro-DMT
• 4-fluoro-5-methoxy-DMT
• 6-Fluoro-DET(6-Fluoro-DET)
• O-4310
• It's worth noting that GR-159897 is based on the same structure.