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Antiinfective agent stubs
CMX521
Другие языки:

    CMX521

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    CMX521
    CMX521 structure.png
    Legal status
    Legal status
    • US: Investigational drug
    Identifiers
    • 4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-methylpyrrolo[2,3-d]pyrimidine-5-carboxamide
    CAS Number
    PubChem CID
    UNII
    Chemical and physical data
    Formula C13H17N5O5
    Molar mass 323.3 g·mol−1
    3D model (JSmol)
    • CC1=NC(=C2C(=CN(C2=N1)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)C(=O)N)N
    • InChI=1S/C13H17N5O5/c1-4-16-10(14)7-5(11(15)22)2-18(12(7)17-4)13-9(21)8(20)6(3-19)23-13/h2,6,8-9,13,19-21H,3H2,1H3,(H2,15,22)(H2,14,16,17)/t6-,8-,9-,13-/m1/s1
    • Key:PMQFVTNOZQVIOK-HTVVRFAVSA-N

    CMX521 is an antiviral drug discovered by Chimerix, which was developed for the treatment of norovirus, though it also shows efficacy against related viral diarrheas such as rotovirus and some sapoviruses, astroviruses and adenoviruses. It is a nucleoside analogue which acts as an inhibitor of viral RNA-dependant RNA polymerase.

    See also


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