Cefsulodin

Cefsulodin

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J01DD03 (WHO)
Identifiers
IUPAC name 4-(aminocarbonyl)-1-[((6R,7R)-2-carboxy-8-oxo-7-{[phenyl(sulfo)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl]pyridinium
CAS Number	62587-73-9 Y Sodium salt: 52152-93-9 Y
PubChem CID	5284530
ChemSpider	4447588 Y
UNII	OV42LHE42B Sodium salt: 2D087186PY Y
KEGG	D02005 Y
ChEMBL	ChEMBL1617285 N
CompTox Dashboard (EPA)	DTXSID6022769
Chemical and physical data
Formula	C22H21N4O8S2+
Molar mass	533.55 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(c3ccccc3)S(=O)(=O)O)C[n+]4ccc(C(=O)N)cc4)C([O-])=O
InChI InChI=1S/C22H20N4O8S2/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34)/t15-,17?,21-/m1/s1 Y Key:SYLKGLMBLAAGSC-IKZMBGHXSA-N Y
NY (what is this?)  (verify)

Cefsulodin is a third-generation cephalosporin antibiotic that is active against Pseudomonas aeruginosa and was discovered by Takeda Pharmaceutical Company in 1977.

TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985.

Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for Yersinia microorganisms. This agar is most often used in water and beverage testing.

Susceptibility data

The following represents MIC susceptibility data for various P. aeruginosa strains:

• Pseudomonas aeruginosa PA13 (resistant strain): 32 μg/ml
• Pseudomonas aeruginosa (wild-type, susceptible): 4 - 8 μg/ml