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Cholesterolosis of gallbladder

Cholesterolosis of gallbladder

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Cholesterolosis of gallbladder
Histopathology of cholesterolosis, with annotated foam cell.jpg
Micrograph of cholesterolosis of the gallbladder, with an annotated foam cell. H&E stain.
Specialty Gastroenterology Edit this on Wikidata

In surgical pathology, strawberry gallbladder, more formally cholesterolosis of the gallbladder and gallbladder cholesterolosis, is a change in the gallbladder wall due to excess cholesterol.

The name strawberry gallbladder comes from the typically stippled appearance of the mucosal surface on gross examination, which resembles a strawberry. Cholesterolosis results from abnormal deposits of cholesterol esters in macrophages within the lamina propria (foam cells) and in mucosal epithelium. The gallbladder may be affected in a patchy localized form or in a diffuse form. The diffuse form macroscopically appears as a bright red mucosa with yellow mottling (due to lipid), hence the term strawberry gallbladder. It is not tied to cholelithiasis (gallstones) or cholecystitis (inflammation of the gallbladder).

Additional images

See also

Further reading

  • Izzo L, Boschetto A, Brachini G, et al. (2001). "["Strawberry" gallbladder: review of the literature and our experience]". Il Giornale di Chirurgia (in Italian). 22 (1–2): 33–6. PMID 11272434.

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