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Antiemetics
Clebopride
Другие языки:

Clebopride

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Clebopride
Clebopride.svg
Clebopride.png
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
  • 4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-
    2-methoxybenzamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.054.424
Chemical and physical data
Formula C20H24ClN3O2
Molar mass 373.88 g·mol−1
3D model (JSmol)
  • Clc1cc(c(OC)cc1N)C(=O)NC3CCN(Cc2ccccc2)CC3
  • InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) checkY
  • Key:BVPWJMCABCPUQY-UHFFFAOYSA-N checkY
  (verify)

Clebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it is a substituted benzamide, closely related to metoclopramide.

A small Spanish study found that more adverse reactions are reported with clebopride than with metoclopramide, particularly extrapyramidal symptoms.


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