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Debrisoquine
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Names | |
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Preferred IUPAC name
3,4-Dihydroisoquinoline-2(1H)-carboximidamide | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider |
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DrugBank |
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ECHA InfoCard | 100.013.155 |
KEGG |
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MeSH | Debrisoquine |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C10H13N3 | |
Molar mass | 175.23032 |
Pharmacology | |
C02CC04 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Debrisoquine is a derivative of guanidine. It is an antihypertensive drug similar to guanethidine. Debrisoquine is frequently used for phenotyping the CYP2D6 enzyme, a drug-metabolizing enzyme.
See also
The guanidine part of the molecule also appears in guanoxan and guanadrel.
- The 7-bromo analog of Debrisoquine is called Guanisoquin.
Sympatholytics (antagonize α-adrenergic vasoconstriction) |
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Other antagonists |
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