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Fcα/μR

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Fc receptor, IgA, IgM, high affinity
Identifiers
Symbol FCAMR, CD351
NCBI gene 83953
HGNC 24692
OMIM 605484
RefSeq NM_032029
UniProt Q96SA2
Other data
Locus Chr. 1 q32.1
Search for
Structures Swiss-model
Domains InterPro

Fcα/μR, also known as is CD351 (Cluster of Differentiation 351), is an Fc receptor that binds IgM with high affinity and IgA with a 10-fold lower affinity. In mice the receptor is expressed on macrophages, follicular dendritic cells, marginal zone B cells, follicular B cells, and kidney tubular epithelial cells. In humans expression has been described on intestinal lamina propria cells, Paneth cells, follicular dendritic cells in tonsils, activated macrophages and some types of pre-germinal centre IgD+/CD38+ B cells.

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