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Fenadiazole
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Fenadiazole

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Fenadiazole
Fenadiazole.svg
Ball-and-stick model of the fenadiazole 3D ball.png molecule
Clinical data
Trade names Hypnazol, Eudormil, Viodor
Other names Fenadiazol; Fenadiazolum; Fenodiazole; Phénadiazole; Phenadiazole; JL-512; J. L. 512; NSC-100729; 2-(o-Hydroxyphenyl)-1,3,4-oxadiazole; 2-(2-Hydroxyphenyl)-1,3,4-oxadiazole; o-1,3,4-Oxadiazol-2-ylphenol
Routes of
administration
By mouth
ATC code
  • None
Identifiers
  • 2-(1,3,4-Oxadiazol-2-yl)phenol
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.206.148
Chemical and physical data
Formula C8H6N2O2
Molar mass 162.148 g·mol−1
3D model (JSmol)
  • C1=CC=C(C(=C1)C2=NN=CO2)O
  • InChI=1S/C8H6N2O2/c11-7-4-2-1-3-6(7)8-10-9-5-12-8/h1-5,11H ☒N
  • Key:OINXXHYENYVYPB-UHFFFAOYSA-N ☒N
  (verify)

Fenadiazole (INN), also known as phénadiazole (DCF) and sold under the brand names Hypnazol, Eudormil, and Viodor, is a hypnotic and sedative medication which has been used to treat insomnia but is no longer marketed. It is described as a non-barbiturate hypnotic with marked or profound hypnotic and sedative properties in animals, variable hypnotic effects in humans (rapidly inducing sleep for 6 to 8 hours), additional anticonvulsant, antithermal, and spasmolytic effects, and a generally well-tolerated profile in humans (at an average dosage of 200 mg/day). The drug was synthesized, pharmacologically characterized, patented, and marketed by the French pharmaceutical company Laboratoires Jacques Logeais between 1960 and 1962. As a hypnotic and sedative, fenadiazole has a unique oxadiazole-based chemical structure. It may be chemically related to certain other hypnotics and sedatives with atypical chemical structures.




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