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Respiratory system drug stubs
Fenleuton
Другие языки:

    Fenleuton

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    Fenleuton
    Fenleuton skeletal.svg
    Clinical data
    Trade names Lofrin
    ATC code
    • none
    Identifiers
    • 1-{4-[3-(4-Fluorophenoxy)phenyl]-3-butyn-2-yl}-1-hydroxyurea
    CAS Number
    ChemSpider
    UNII
    KEGG
    Chemical and physical data
    Formula C17H15FN2O3
    Molar mass 314.316 g·mol−1
    3D model (JSmol)
    • CC(C#Cc1cccc(c1)Oc2ccc(cc2)F)N(C(=O)N)O
    • InChI=InChI=1S/C17H15FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-4,7-12,22H,1H3,(H2,19,21)
    • Key:MWXPQCKCKPYBDR-UHFFFAOYSA-N

    Fenleuton (trade name Lofrin) is a drug that acts as a 5-lipoxygenase inhibitor and inhibits leukotriene (LTB4, LTC4, LTD4, and LTE4) formation. It has been studied for potential use in veterinary medicine to treat respiratory diseases such as chronic obstructive pulmonary disease (COPD) in horses.



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