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Gepotidacin
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Clinical data | |
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Other names | GSK2140944 |
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ECHA InfoCard | 100.249.088 |
Chemical and physical data | |
Formula | C24H28N6O3 |
Molar mass | 448.527 g·mol−1 |
3D model (JSmol) | |
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Gepotidacin (INN) is an experimental antibiotic that acts as a topoisomerase type II inhibitor. It is being studied for the treatment of uncomplicated urinary tract infection (acute cystitis) and infection with Neisseria gonorrhoeae (gonorrhea), including multidrug resistant strains.
Antifolates (inhibit bacterial purine metabolism, thereby inhibiting DNA and RNA synthesis) |
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Quinolones (inhibit bacterial topoisomerase and/or DNA gyrase, thereby inhibiting DNA replication) |
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Anaerobic DNA inhibitors |
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RNA synthesis |
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