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Gilvocarcin V
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Names | |
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IUPAC name
4-[3,4-dihydroxy-5-(1-hydroxyethyl)oxolan-2-yl]-8-ethenyl-1-hydroxy-10,12-dimethoxynaphtho[1,2-c]isochromen-6-one
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Other names
NSC348115, Anandimycin A, Toromycin B, Antibiotic 1072B
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C27H26O9 | |
Molar mass | 494.496 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Gilvocarcin V is an antitumor agent and an antibiotic which is active against Gram-positive bacteria with the molecular formula C27H26O9.Gilvocarcin V is produced by the bacterium Streptomyces griseoflavus and other Streptomyces bacteria. Gilvocarcin V is a strong inhibitor of the DNA synthesis.
Further reading
- Gillum, Karen D. (1988). Lethal and Mutagenic Effects of Antitumor Agent Gilvocarcin V Photosensitization on Escherichia Coli K-12/343/120. Texas Southern University.
- Publishers, Bentham Science (November 1997). Current Organic Chemistry. Bentham Science Publishers. p. 408.
- Transferases—Advances in Research and Application: 2012 Edition. ScholarlyEditions. 26 December 2012. p. 137. ISBN 978-1-4649-9789-1.
- Diana, Patrizia; Cirrincione, Girolamo (9 February 2015). Biosynthesis of Heterocycles: From Isolation to Gene Cluster. John Wiley & Sons. p. 585. ISBN 978-1-118-02867-4.