| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Mouse |
| Target | Glutamate carboxypeptidase II |
| Clinical data | |
| Trade names | Prostascint |
| ATC code | |
| Identifiers | |
| CAS Number |
|
| ChemSpider |
|
| UNII | |
| ChEMBL | |
  (what is this?) (verify)
| |
Indium (111In) capromab pendetide (trade name Prostascint) is used to image the extent of prostate cancer. Capromab is a mouse monoclonal antibody which recognizes a protein found on both prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA. Pendetide acts as a chelating agent for the radionuclide indium-111. Following an intravenous injection of Prostascint, imaging is performed using single-photon emission computed tomography (SPECT).
Early trials with yttrium (90Y) capromab pendetide were also conducted.