| Inverted papilloma | |
|---|---|
| Other names | Ringertz tumour |
 | |
| Micrograph of an inverted papilloma of the urinary bladder. H&E stain. | |
| Specialty |
Oncology 
|
An inverted papilloma, also known as Ringertz tumour, is a type of tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra). When it occurs in the nose or sinuses, it may cause symptoms similar to those caused by sinusitis, such as nasal congestion. When it occurs in the urinary tract, it may cause blood in the urine.
Diagnosis
Inverted papillomas are definitively diagnosed by histologic examination. However, magnetic resonance imaging (MRI) may show a characteristic feature described as a convoluted cerebriform pattern (CCP). A retrospective study published in the American Journal of Neuroradiology concluded that identification of CCP by MRI in a patient with a nasal tumor made the diagnosis of Inverted papilloma quite likely. The study reported the sensitivity and specificity to be 100% and 87% respectively. CCP can be associated with other malignant tumors as well.
Treatment
Medial maxillectomy is the treatment of choice.
History
Inverted papillomae were first described by Nils Ringertz in 1938. He reported their microscopic appearance and their tendency to grow into the connective tissue stroma.
Additional images
Histopathology representing an inverted papilloma of the urinary bladder that was cystoscopically resected. Hematoxylin and eosion stain.
Histopathology representing an inverted papilloma of the urinary bladder that was cystoscopically resected. Hematoxylin and eosion stain.
Histopathology representing an inverted papilloma of the urinary bladder that was cystoscopically resected. Hematoxylin and eosion stain.
Inverted Schneiderian Papilloma of the Nasal Cavity.
Inverted Schneiderian Papilloma of the Nasal Cavity with Abundant intraepithelial microabscesses.
External links
- Inverted papilloma entry in the public domain NCI Dictionary of Cancer Terms
This article incorporates public domain material from Dictionary of Cancer Terms. U.S. National Cancer Institute.