Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
CB1 receptor agonists
JWH-367
Другие языки:

    JWH-367

    Подписчиков: 0, рейтинг: 0
    JWH-367
    JWH-367.svg
    Legal status
    Legal status
    Identifiers
    • [5-(3-methoxyphenyl)-1-pentylpyrrol-3-yl]-naphthalen-1-ylmethanone
    CAS Number
    PubChem CID
    ChemSpider
    Chemical and physical data
    Formula C27H27NO2
    Molar mass 397.518 g·mol−1
    3D model (JSmol)
    • CCCCCN1C=C(C=C1C2=CC(=CC=C2)OC)C(=O)C3=CC=CC4=CC=CC=C43
    • InChI=1S/C27H27NO2/c1-3-4-7-16-28-19-22(18-26(28)21-12-8-13-23(17-21)30-2)27(29)25-15-9-11-20-10-5-6-14-24(20)25/h5-6,8-15,17-19H,3-4,7,16H2,1-2H3 checkY
    • Key:RGYBGMOZXHKLRI-UHFFFAOYSA-N checkY

    JWH-367 ([5-(3-methoxyphenyl)-1-pentylpyrrol-3-yl]-naphthalen-1-ylmethanone) is a synthetic cannabinoid from the naphthoylpyrrole family which acts as an agonist of the CB1 (Ki = 53 ± 2nM) and CB2 (Ki = 23 ± 1nM) receptors, binding ~2.3 times stronger to the CB2 receptor than to the CB1 receptor. JWH-367 was first synthesized in 2006 by John W. Huffman and colleagues to examine the nature of ligand binding to the CB1 receptor.

    Legality

    In the United States JWH-367 is not federally scheduled, although some states have passed legislation banning the sale, possession, and manufacture of JWH-367.

    In Canada, JWH-367 and other naphthoylpyrrole-based cannabinoids are Schedule II controlled substances under the Controlled Drugs and Substances Act.

    In the United Kingdom, JWH-367 and other naphthoylpyrrole-based cannabinoids are considered Class B drugs under the Misuse of Drugs Act 1971.

    See also



    Новое сообщение