List of adverse effects of venlafaxine

The following list shows the rates of adverse symptoms seen in people taking venlafaxine.

Very common (>10% incidence)

• Headache — an often transient side effect that is common to most serotonin reuptake inhibitors and that most often occurs at the beginning of therapy or after a dose escalation.
• Nausea — an adverse effect that is more common with venlafaxine than with the SSRIs. Usually transient and less severe in those receiving the extended release formulations.
• Insomnia
• Asthenia (weakness)
• Dizziness
• Ejaculation disorder — sexual side effects can be seen with virtually any antidepressant, especially those that inhibit the reuptake of serotonin (including venlafaxine).
• Somnolence
• Dry mouth
• Sweating
• Withdrawal

Common (1–10% incidence)

Uncommon (0.1-1% incidence)

Rare (0.01–0.1% incidence)

• Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
• Thrombocytopenia
• Prolonged bleeding time
• Seizures
• Mania
• Neuroleptic malignant syndrome (NMS)
• Serotonin syndrome
• Akathisia/psychomotor restlessness
• Urinary incontinence

Very rare (<0.01% incidence)