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List of breast cancer cell lines
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    List of breast cancer cell lines

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    Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer research.

    List of cell lines

    Cell line Primary tumor Origin of cells Estrogen receptors Progesterone receptors ERBB2 amplification Mutated TP53 Tumorigenic in mice Reference External links
    600MPE Invasive ductal carcinoma + Cellosaurus
    AMJ13 Invasive ductal carcinoma Primary Yes Yes No - - Cellosaurus
    AU565 Adenocarcinoma + Cellosaurus
    BT-20 Invasive ductal carcinoma Primary No No No Yes Yes Cellosaurus
    BT-474 Invasive ductal carcinoma Primary Yes Yes Yes Yes Yes Cellosaurus
    BT-483 Invasive ductal carcinoma + + Cellosaurus
    BT-549 Invasive ductal carcinoma + Cellosaurus
    Evsa-T Invasive ductal carcinoma, mucin-producing, signet-ring type Metastasis (ascites) No Yes ? Yes ? Cellosaurus
    Hs578T Invasive ductal carcinoma Primary No No No Yes No Cellosaurus
    MCF-7 Invasive ductal carcinoma Metastasis (pleural effusion) Yes Yes No No (wild-type) Yes (with estrogen supplementation) Cellosaurus
    MDA-MB-231 Adenocarcinoma Metastasis (pleural effusion) No No No Yes Yes Cellosaurus
    SkBr3 Invasive ductal carcinoma Metastasis (pleural effusion) No No Yes Yes No Cellosaurus
    T-47D Invasive ductal carcinoma Metastasis (pleural effusion) Yes Yes No Yes Yes (with estrogen supplementation) Cellosaurus
    ZR-75-1 Invasive ductal carcinoma Cellosaurus

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