List of immunofluorescence findings for autoimmune bullous conditions
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List of immunofluorescence findings for autoimmune bullous conditions
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See also: List of cutaneous conditions
This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources.
Several cutaneous conditions can be diagnosed with the aid of immunofluorescence studies.
Cutaneous conditions with positive direct or indirect immunofluorescence when using salt-split skin include:
| Condition | Antibody isotype(s) deposited | Localization of antibody with use of salt-split skin |
|---|---|---|
| Antiepilegrin cicatricial pemphigoid | IgG | Dermal |
| Bullous lupus erythematosus | Dermal | |
| Bullous pemphigoid | IgG | Epidermal |
| Cicatricial pemphigoid | IgG | Epidermal |
| Epidermolysis bullosa acquisita | IgG | Dermal |
| Linear IgA bullous dermatosis | IgA | Epidermal |
| Orf-induced immunobullous disease | IgG | Dermal |
| Pemphigoid gestationis | IgG | Epidermal |
For several subtypes of pemphigus a variety of substrates are used for indirect immunofluorescence:
| Pemphigus variant | Substrate |
|---|---|
| Pemphigus foliaceous | Guinea pig esophagus |
| Pemphigus vulgaris | Monkey esophagus |
| IgA pemphigus | Cultured skin |
| Paraneoplastic pemphigus | Rat bladder |
See also
- List of cutaneous conditions
- List of genes mutated in cutaneous conditions
- List of cutaneous conditions caused by mutations in keratins
- Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. ISBN 1-4160-2999-0.
- James, William D.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.