A number of online neuroscience databases are available which provide information regarding gene expression, neurons, macroscopic brain structure, and neurological or psychiatric disorders. Some databases contain descriptive and numerical data, some to brain function, others offer access to 'raw' imaging data, such as postmortem brain sections or 3D MRI and fMRI images. Some focus on the human brain, others on non-human.
As the number of databases that seek to disseminate information about the structure, development and function of the brain has grown, so has the need to collate these resources themselves. As a result, there now exist databases of neuroscience databases, some of which reach over 3000 entries.
Neuroscience databases
| Name | Description | Organism | Level (gene, neuron, macroscopic) | Data (MRI, fMRI, images, descriptive, numerical) | Disorder | Register to view data? | Ref. | |
|---|---|---|---|---|---|---|---|---|
| Allen Brain Atlas | Atlas, stained sections from brains showing development and gene expression | Mouse, Human | Macroscopic, Gene | Images | Healthy | No | ||
| Alzheimer's Disease Neuroimaging Initiative (ADNI) | Structural MRI images | Human | Macroscopic | MRI datasets | Healthy and Alzheimer's disease | Yes | ||
| Big Brain | 3D reconstruction of complete brain from cell-body stained histology sections at 20 micron isotropic resolution | Human | Microscopic | Images | Healthy | No | ||
| BIRN fMRI and MRI data | fMRI, MRI scans and atlases for human and mouse brains | Mouse, Human | Multilevel: brain regions, connections, neurons, gene expression patterns | MRI datasets, fMRI datasets | Healthy, Elderly | No | ||
| Bipolar Disorder Neuroimaging Database | Meta-analysis and database of MRI studies | Human | Macroscopic | Descriptive, numerical | Bipolar Disorder | No | ||
| Brain Architecture Management System | Online resource for information about neural circuitry | Rat, mouse, human | Multilevel: brain regions, connections, neurons, gene expression patterns | Descriptive, numerical | Healthy | No | ||
| Brain Cloud | Gene expression in the human prefrontal cortex | Human | Gene expression patterns | Descriptive, numerical | Healthy | No | ||
| Brain-CODE | A multi-modal, cross-disorder platform for integrated neuroscience research and data by the Ontario Brain Institute. | Human, Animal | Multimodal datasets (clinical, imaging, molecular, etc.) | Descriptive, numerical, imaging, molecular, genetics | Neurodevelopmental, Cerebral Palsy, Epilepsy, Depression, Neurodegeneration, Concussion | Yes | ||
| Brain-Development.org | Structural MRI images and Atlases | Human | Macroscopic | MRI datasets | Fetuses, healthy and prematurely born neonates | Yes | ||
| Braingraph.org | Braingraphs computed from the Human Connectome Project data | Human | Macroscopic, up to 1015 nodes | directed and undirected graphs in anatomically annotated GraphML format | Healthy | No | ||
| Braininfo | Atlas, schematic atlas of Macaca fascicularis | Macaque | Macroscopic | Schematic images | Healthy | Yes | ||
| Brain Machine Interface Platform | Different types of data related to brain machine interface | Human, Monkey | Macroscopic, Neuron | Images, Numerical | Healthy | No | ||
| BrainMap.org | fMRI coordinate database | Human | Macroscopic | Descriptive | Healthy | Yes | ||
| BrainMaps | Atlas, high resolution stained sections from brains | Human, primate and non-primate (14 species in all) | Neuron and Macroscopic | Images | Healthy | No | ||
| Brain/MINDS Dataportal | Atlas, in-vivo and ex-vivo MRI scans, ECoG recordings | Common Marmoset, Human | Macroscopic | Images | Healthy | No | ||
| Brede Database | fMRI and PET coordinate database | Human | Macroscopic | Descriptive | Healthy | No | ||
| Brainmuseum.org / MSU Brain Biodiversity Bank | Atlas, stained sections from brains and MRI images | Human and 62 other species | Macroscopic | Images | Healthy | No | ||
| Brainomics/Localizer | fMRI and MRI scans, behavioral data | Human | Macroscopic | Images, Numerical | Healthy | No | ||
| BuzLabDB: The Buzsaki Lab Databank | Electrophysiological recordings performed in freely moving rats and mice collected by investigators in the Buzsaki Lab | Mice and rats | Multiscale | Spike trains, LFP, Raw ephys data | Healthy | No | ||
| Caltech Subcortical Atlas | MRI scans | Human | Macroscopic | MRI | Healthy | No | ||
| Cambridge Centre for Ageing and Neuroscience (Cam-CAN) | MRI, fMRI, MEG data for ~700 population-derived healthy adults aged 18-88 | Human | Macroscopic | Images, Descriptive, Numerical | Healthy | No | ||
| The Cancer Imaging Archive | MRI, CT, and PET imaging of cancer patients with supporting clinical data (in many cases) | Human | Macroscopic | Images, Descriptive, Numerical | Cancer | No | ||
| Cerebellar Development Transcriptome Database | Atlas, stained sections from mouse brains showing cerebellar development and gene expression | Mouse | Macroscopic, Gene | Images | Healthy | No | ||
| Collaborative Research in Computational Neuroscience (CRCNS.org) | Many kinds of neuroscience results that are relevant for modeling | Human and several other species | Multiscale | Spike trains, LFP, MUA, MRI | Healthy | Yes | ||
| DANDI: Distributed Archives for Neurophysiology Data Integration | cellular neurophysiology data including electrophysiology, optophysiology, and behavioral time-series, and images from immunostaining experiments | Human and several other species | Multiscale | Spike trains, LFP, MUA, MRI | Healthy | |||
| Database for Reaching Experiments And Models (DREAM) | Reaching data (behavioral, generalization, adaptation, learning, spike, fMRI, uncertainty) | Human and monkey | Macroscopic | Kinematic, Spike, fMRI | Healthy | Yes | ||
| The fMRI Data Center | fMRI datasets from published studies | Human | Macroscopic | fMRI datasets | Healthy | Yes | ||
| GLIMPS Project (GLucose IMaging in Parkinsonian Syndromes) | International FDG-PET scan neurodegenerative disease database | Human | Macroscopic | FDG-PET images | Parkinson's disease (PD), Alzheimer's disease (AD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), etc. | Yes | ||
| Hippocampome Portal | Circuitry, neural types, electrophysiology | Adult human | Neuron | Cell morphology, electrophysiology, region makeup, connectivity | Healthy | Yes | ||
| IBA: Infant Brain Atlas | Infant brain atlases from 2 weeks to 2 years of age | Human infants | Macroscopic, microscopic, brain regions | MRI | Healthy | No | ||
| International Epilepsy Electrophysiology Database (IEEG.org) | EEG, metadata, imaging, annotations on data | Humans and animal models of epilepsy | EEG, local fields, micro-ECoG | Electrophysiology | Non-healthy, several healthy | Yes | ||
| International Neuroimaging Data-sharing Initiative (INDI) | Functional connectivity data from many different groups | Invertebrates (47 species in all) | Macroscopic | Functional connectivity | Healthy, non-healthy | Yes | ||
| Invertebrate Brain Platform | Photos of dissections of invertebrates nervous systems | Invertebrates (47 species in all) | Macroscopic | Photos | Healthy | No | ||
| In vivo human phantom | Ultrahigh resolution MRI data of a single participant including 150 μm ToF angiography, 250 μm T1-weighted MPRAGE, 330 μm QSM, 450 μm T2-weighted TSE, 800 μm DTI, one hour continuous 1.8 mm rs-fMRI and structural data acquired over more than a decade | Human | Mesoscopic | Structural MRI with various contrasts, microstructure MRI and functional MRI | Healthy | No | ||
| JuBrain atlas | Probabilistic cytoarchitectonic 3D maps of the human brain | Human | Mesoscopic | Structural | Healthy | No | ||
| Kymata Atlas | Functional atlas of the human cortex | Human | Macroscopic | Functional | Healthy | No | ||
| Major Depressive Disorder Neuroimaging Database | Meta-analysis and database of MRI studies | Human | Macroscopic | Descriptive, numerical | Major Depressive Disorder | No | ||
| Marmoset Gene Atlas | Gene expression in the common marmoset whole brain | Common Marmoset | Macroscopic, Gene | Images | Healthy | No | ||
| Mouse Brain Library | Atlas, stained sections from mouse brains | Mouse | Macroscopic | Images | Healthy | No | ||
| NeuroData | Volumetric datasets, atlases, and connectomics research | Multiple | Multiscale | Images (3D, 4D) | Various | No | ||
| Neuroelectro.org | Electrophysiology of neurons | Human, others | Neuron | Electrophysiological properties and data | Healthy | No | ||
| Neuromorpho.org | 3D models of real neurons | Human, rat, mouse, monkey, others | Neuron | Images and 3D data | Healthy | No | ||
| Neuromorphometrics.com | Manually labeled MRI Brain Scans | Human | Macroscopic | T1-weighted MRI, labeled volumes | Healthy | No | ||
| NeuronDB | Database of Neuron properties and classification | Human | Neuron | Descriptive | Healthy | No | ||
| Neuroimaging Tools and Resources Collaboratory (NITRC) | Award-winning free collaboratory with over 1000 neuroinformatics software tools, imaging datasets, and community resources including forums and events. | Human, mouse, rat, other | Microscopic, macroscopic | Datasets | Healthy and diseased | No | ||
| Open Access Series of Imaging Studies (OASIS) | Structural MRI images | Human | Macroscopic | MRI datasets | Healthy and Alzheimer's disease | Yes | ||
| Open Connectome Project | Database of different circuitry frameworks and neuroimaging datasets, including volumetric datasets, atlases, and connectomics research | Human, mouse, bat, zebrafish, insect, other | Multilevel: brain regions, connections, neurons, gene expression patterns | Images and 3D data | Healthy | No | ||
| OpenNeuro | Large and diverse collection of raw data from various research studies distributed under permissive licenses (CC0 and CC BY). All datasets are formatted according to the same format (Brain Imaging Data Structure) and can be accessed via Amazon S3. | Human | Macroscopic | Functional, structural, diffusion MRI, and Magnetoencephalography datasets | Healthy and various diseases | No | ||
| Open MEG Archive (OMEGA) | Magnetoencephalography, structural MRI datasets, and demographics | Human | Macroscopic | MEG, T1 MRI datasets, demographic data | Healthy, ADHD, Traumatic brain injury | Yes | ||
| The PAIN Repository | Structural, Diffusion and Functional MRI datasets | Human | Human Macroscopic | MRI datasets and Metadata | Healthy and Pain Conditions | Yes | ||
| Pig Brain Atlas | Pig Brain Atlas is a three-dimensional MRI-based averaged brain and atlas of the neonatal piglet (Sus scrofa). | Pig (Sus scrofa) | Macroscopic | Structural MRI | Healthy | Yes | ||
| Primate Cell Type Database | PrimateDatabase.com, a publicly available web-accessible archive of intracellular patch clamp recordings and highly detailed three-dimensional digital reconstructions of neuronal morphology. | Non-human primate and human | Neuron | Electrophysiology, Morphology and 3-d Reconstructions | Healthy | No | ||
| SchizConnect | SchizConnect is an open, public search-and-download virtual database for schizophrenia neuroimaging (MRI) images and related data. | Human | Macroscopic | Structural, Diffusion and Functional MRI datasets, cognitive and clinical assessments | Schizophrenia (+ siblings), Bipolar Disorder, Controls (+ siblings) | Yes | ||
| Temple EEG Database | Over 30,000 clinical EEGs and accompanying neurologist reports | Human | Macroscopic | EEG | Healthy and various diseases | Yes | ||
| Ultrahigh resolution T1-weighted whole brain MR dataset | T1-weighted MR data acquired using prospective motion correction at an ultrahigh isotropic resolution of 250 µm. | Human | Mesoscopic | Structural MRI dataset including scanner's raw to processed data | Healthy | No | ||
| UNC-Wisconsin Neurodevelopment Rhesus MRI Database | Structural and Diffusion Weighted MRI images in Native and Atlas Space | Macaque | Macroscopic | MRI datasets | Healthy | No | ||
| Whole Brain Atlas | Atlas, Structural MRI images and PET images | Human | Macroscopic | Images | Healthy and various diseases | No | ||
| NeuroVault | Unthresholded statistical maps from MRI and PET studies. | Human | Macroscopic | Images | Healthy and various diseases | No |
Databases of neuroscience databases
| Name | Description | Organism | Level (gene, neuron, macroscopic) | Data (MRI, fMRI, images, descriptive, numerical) | Disorder | Register to view data? | Ref. |
|---|---|---|---|---|---|---|---|
| Neuroscience Information Framework | A meta database of neuroscience-relevant data incorporating over 100 databases. | Human, mouse, rat, worm | Microscopic, macroscopic | Datasets | Healthy and diseased | No |
Neuroscience article aggregators
Neuroscience feed at RightRelevance.
