Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
Antidepressant
Lortalamine
Другие языки:

Lortalamine

Подписчиков: 0, рейтинг: 0
Lortalamine
Lortalamine.svg
Lortalamine ball-and-stick model.png
Clinical data
Routes of
administration		 Oral
ATC code
  • None
Pharmacokinetic data
Elimination half-life 5 hours
Excretion Renal (98%)
Identifiers
  • 8-chloro-1,2,3,4,10,10a-hexahydro-2-methyl-4a,10-(iminoethano)-4aH-[1]-benzopyrano[3,2-c]-pyridin-12-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
Formula C15H17ClN2O2
Molar mass 292.76 g·mol−1
3D model (JSmol)
  • Clc1ccc2O[C@]34NC(=O)C[C@@H](c2c1)[C@H]4CN(C)CC3

Lortalamine (LM-1404) is an antidepressant which was synthesized in the early 1980s. It acts as a potent and highly selective norepinephrine reuptake inhibitor. Lortalamine was under development for clinical use but was shelved, likely due to the finding that it produced ocular toxicity in animals. It has been used to label the norepinephrine transporter in positron emission tomography studies.

See also


Новое сообщение