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Drugs acting on the blood and blood forming organs
Lusutrombopag
Другие языки:

    Lusutrombopag

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    Lusutrombopag
    Lusutrombopag.svg
    Clinical data
    Pronunciation loo" soo trom' boe pag
    Trade names Mulpleta, Mulpleo
    AHFS/Drugs.com Monograph
    MedlinePlus a618043
    License data
    Routes of
    administration    		 By mouth
    ATC code
    Legal status
    Legal status
    • US: ℞-only
    • EU: Rx-only
    • In general: ℞ (Prescription only)
    Identifiers
    • (E)-3-[2,6-Dichloro-4-[[4-[3-[(1S)-1-hexoxyethyl]-2-methoxyphenyl]-1,3-thiazol-2-yl]carbamoyl]phenyl]-2-methylprop-2-enoic acid
    CAS Number
    PubChem CID
    DrugBank
    ChemSpider
    UNII
    KEGG
    ChEMBL
    Chemical and physical data
    Formula C29H32Cl2N2O5S
    Molar mass 591.54 g·mol−1
    3D model (JSmol)
    • CCCCCCO[C@@H](C)c1cccc(-c2csc(NC(=O)c3cc(Cl)c(/C=C(\C)C(=O)O)c(Cl)c3)n2)c1OC
    • InChI=1S/C29H32Cl2N2O5S/c1-5-6-7-8-12-38-18(3)20-10-9-11-21(26(20)37-4)25-16-39-29(32-25)33-27(34)19-14-23(30)22(24(31)15-19)13-17(2)28(35)36/h9-11,13-16,18H,5-8,12H2,1-4H3,(H,35,36)(H,32,33,34)/b17-13+/t18-/m0/s1 checkY
    • Key:NOZIJMHMKORZBA-KJCUYJGMSA-N checkY
     ☒NcheckY (what is this?)

    Lusutrombopag, sold under the brand name Mulpleta among others, is a medication that has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts) such as thrombocytopenia associated with chronic liver disease in patients prior to elective invasive procedures. It is being manufactured and marketed in Japan by Shionogi. It was approved by the U.S. Food and Drug Administration (FDA) in July 2018, and NICE in January 2020.

    It was approved for medical use in the European Union in February 2019.

    External links

    • "Lusutrombopag". Drug Information Portal. U.S. National Library of Medicine.



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