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Abandoned drugs
Meclorisone
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    Meclorisone

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    Meclorisone
    Meclorisone.svg
    Clinical data
    Other names NSC-92353; 16α-Methyldichlorisone; 9α,11β-Dichloro-17α,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione
    Drug class Corticosteroid; Glucocorticoid
    Identifiers
    • (8S,9R,10S,11S,13S,14S,16R,17R)-9,11-Dichloro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C22H28Cl2O4
    Molar mass 427.36 g·mol−1
    3D model (JSmol)
    • C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)Cl)Cl)C
    • InChI=1S/C22H28Cl2O4/c1-12-8-16-15-5-4-13-9-14(26)6-7-19(13,2)21(15,24)17(23)10-20(16,3)22(12,28)18(27)11-25/h6-7,9,12,15-17,25,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
    • Key:OKWSMPYQIYKVDC-CXSFZGCWSA-N

    Meclorisone (developmental code name NSC-92353) is a synthetic glucocorticoid corticosteroid which was never marketed.




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