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Megazol
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Megazol

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Megazol
Megazol.svg
Clinical data
ATC code
  • None
Identifiers
  • 5-(1-methyl-5-nitro-1H-imidazol-2-yl)-1,3,4-thiadiazol-2-amine
CAS Number
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C6H6N6O2S
Molar mass 226.21 g·mol−1
3D model (JSmol)
  • Cn1c(cnc1c2nnc(s2)N)[N+](=O)[O-]

Megazol (CL 64855) is a nitroimidazole based drug that cures some protozoan infections.

A study of nitroimidazoles found the drug extremely effective against T. cruzi and T. brucei which cause Chagas disease and African sleeping sickness, respectively. The drug is considerably more effective than standard benznidazole therapy (for Chagas) which is considered the gold standard. This is despite that other nitroimidazoles proved ineffective against these pathogens.


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