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Minaprine

Minaprine

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Minaprine
Minaprine.svg
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Elimination half-life 2-2.5 hours
Identifiers
  • 4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.043.012
Chemical and physical data
Formula C17H22N4O
Molar mass 298.390 g·mol−1
3D model (JSmol)
  • CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3
 ☒NcheckY (what is this?)  (verify)

Minaprine (INN, USAN, BAN) (brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.

A study found that it acts as a reversible inhibitor of MAO-A (RIMA) in rats. In a study it has also been found to weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.


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