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List of IARC Group 2B Agents - Possibly carcinogenic to humans
Mutagen X
Другие языки:

Mutagen X

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Mutagen X
Skeletal formula of mutagen X
Space-filling model of the mutagen X molecule
Names
IUPAC name
3-Chloro-4-(dichloromethyl)-5-hydroxy-5H-furan-2-one
Other names
Mutagen X
MX
Identifiers
3D model (JSmol)
ChemSpider
EC Number
  • 253-575-7
KEGG
PubChem CID
UNII
  • InChI=1S/C5H3Cl3O3/c6-2-1(3(7)8)4(9)11-5(2)10/h3-4,9H ☒N
    Key: WNTRMRXAGJOLCU-UHFFFAOYSA-N ☒N
  • InChI=1/C5H3Cl3O3/c6-2-1(3(7)8)4(9)11-5(2)10/h3-4,9H
    Key: WNTRMRXAGJOLCU-UHFFFAOYAU
  • O=C1OC(O)C(C(Cl)Cl)=C1Cl
Properties
C5H3Cl3O3
Molar mass 217.43 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Mutagen X (MX), or 3-chloro-4-(dichloromethyl)-5-hydroxy-5H-furan-2-one, is a byproduct of the disinfection of water by chlorination. MX is produced by reaction of chlorine with natural humic acids.

MX is found in chlorinated drinking water all over the world and is an environmental carcinogen that is known to cause several types of cancer in rats when present in large enough concentrations. It is listed by the International Agency for Research on Cancer as a group 2B carcinogen meaning it is "possibly carcinogenic to humans". Although the concentration of MX in drinking water is typically 100- to 1000-fold lower than other common byproducts of water chlorination such as trihalomethanes, MX might play a role in the increased cancer risks that have been associated with the consumption of chlorinated water because of its potency in inducing DNA damage.

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