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Enzyme inhibitor
NV-5440
Другие языки:

    NV-5440

    Подписчиков: 0, рейтинг: 0
    NV-5440
    NV-5440 structure.png
    Identifiers
    • 2-[4-[5-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-2,4-dimethylbenzoyl]piperazin-1-yl]benzenesulfonamide
    CAS Number
    PubChem CID
    ChemSpider
    Chemical and physical data
    Formula C31H36N6O3S
    Molar mass 572.73 g·mol−1
    3D model (JSmol)
    • CC1=CC(=C(C=C1CN2CCN(CC2)C3=CC=CC=C3C#N)C(=O)N4CCN(CC4)C5=CC=CC=C5S(=O)(=O)N)C
    • InChI=1S/C31H36N6O3S/c1-23-19-24(2)27(20-26(23)22-34-11-13-35(14-12-34)28-8-4-3-7-25(28)21-32)31(38)37-17-15-36(16-18-37)29-9-5-6-10-30(29)41(33,39)40/h3-10,19-20H,11-18,22H2,1-2H3,(H2,33,39,40)
    • Key:BREWSTIKWAQLCH-UHFFFAOYSA-N

    NV-5440 is a drug which acts as both a non-specific inhibitor of the glucose transporters and also a selective inhibitor of mTORC1, with no significant action at the related mTORC2 subtype. Compounds of this type have potential application in the treatment of cancer, and it is also used for research into the links between calorie restriction and longevity.



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