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Ornidazole
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Not to be confused with ronidazole.
Clinical data | |
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Trade names | Xynor |
AHFS/Drugs.com | International Drug Names |
Routes of administration |
Oral |
ATC code | |
Pharmacokinetic data | |
Metabolism | Via liver |
Elimination half-life | 12-13 hours |
Excretion | Urine (63%) and Feces (22%) |
Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider |
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UNII | |
KEGG |
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ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.037.099 |
Chemical and physical data | |
Formula | C7H10ClN3O3 |
Molar mass | 219.63 g·mol−1 |
3D model (JSmol) | |
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NY (what is this?) (verify) |
Ornidazole is an antibiotic used to treat protozoan infections. A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohydrin. Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated; however there are concerns of lower relative efficacy.
It was first introduced for treating trichomoniasis before being recognized for its broad anti-protozoan and anti-anaerobic-bacterial capacities. has also been investigated for use in Crohn's disease after bowel resection.
Antifolates (inhibit bacterial purine metabolism, thereby inhibiting DNA and RNA synthesis) |
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Quinolones (inhibit bacterial topoisomerase and/or DNA gyrase, thereby inhibiting DNA replication) |
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Anaerobic DNA inhibitors |
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RNA synthesis |
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Other |
Entamoeba |
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Authority control: National |
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