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Pentedrone

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Pentedrone
Pentedrone.svg
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • (±)-1-phenyl-2-(methylamino)pentan-1-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard 100.231.338
Chemical and physical data
Formula C12H17NO
Molar mass 191.274 g·mol−1
3D model (JSmol)
  • O=C(C(CCC)NC)C1=CC=CC=C1
  • InChI=1S/C12H17NO/c1-3-7-11(13-2)12(14)10-8-5-4-6-9-10/h4-6,8-9,11,13H,3,7H2,1-2H3 checkY
  • Key:WLIWIUNEJRETFX-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Pentedrone (also known as α-methylaminovalerophenone) is a stimulant of the cathinone class that has been sold as a designer drug and has been found since 2010 as an ingredient in a number of "bath salt" mixes sold as legal highs.

Pharmacology

Pentedrone acts as a norepinephrine-dopamine reuptake inhibitor without causing their release, the same mechanism of action as methylphenidate.

Side effects

Pentedrone has been linked to at least one death where it was combined with α-PVP and caused heart failure.

Detection

A forensic standard of Pentedrone is available, and the compound has been posted on the Forendex website of potential drugs of abuse.

Legal status

On January 28, 2014, the DEA listed it, along with nine other synthetic cathinones, on the Schedule 1 with a temporary ban, effective February 27, 2014.

Pentedrone is an Anlage II controlled drug in Germany.

As of October 2015 Pentedrone is a controlled substance in China.

Pentedrone is banned in the Czech Republic.

See also



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