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Antihypertensive
Pildralazine
Другие языки:

Pildralazine

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Pildralazine
Pildralazine.svg
Clinical data
Other names ISF-2123
Routes of
administration		 Oral
ATC code
  • None
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 1-[(6-Hydrazinylpyridazin-3-yl)(methyl)amino]propan-2-ol
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C8H15N5O
Molar mass 197.242 g·mol−1
3D model (JSmol)
  • n1nc(NN)ccc1N(C)CC(O)C
  • InChI=1S/C8H15N5O/c1-6(14)5-13(2)8-4-3-7(10-9)11-12-8/h3-4,6,14H,5,9H2,1-2H3,(H,10,11)
  • Key:KYIAWOXNPBANEW-UHFFFAOYSA-N

Pildralazine (Atensil), also known as propyldazine or propildazine, is an antihypertensive and vasodilator.

Synthesis

Thieme Synthesis: Patent:

The reaction between 3,6-Dichloropyridazine [141-30-0] (1) and 1-(Methylamino)-2-propanol [16667-45-1] (2) gives CID:12237595 (3). Reaction with hydrazine completes the synthesis of Pidralazine (4).


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