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Experimental drugs
S-18986
Другие языки:

S-18986

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S-18986
S-18986.svg
Legal status
Legal status
Identifiers
  • (S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C10H12N2O2S
Molar mass 224.28 g·mol−1
3D model (JSmol)
  • C1C[C@@H]2NS(=O)(=O)C3=CC=CC=C3N2C1
  • InChI=1S/C10H12N2O2S/c13-15(14)9-5-2-1-4-8(9)12-7-3-6-10(12)11-15/h1-2,4-5,10-11H,3,6-7H2/t10-/m1/s1 ☒N
  • Key:MNTIJYGEITVWHU-SNVBAGLBSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

S-18986 is a positive allosteric modulator of the AMPA receptor related to cyclothiazide. It has nootropic and neuroprotective effects in animal studies, and induces both production of BDNF and AMPA-mediated release of noradrenaline and acetylcholine in the hippocampus and frontal cortex of the brain.

See also



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