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Drugs acting on the cardiovascular system
Sulmazole
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    Sulmazole

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    Sulmazole
    Sulmazole.svg
    Identifiers
    • 2-(2-Methoxy-4-methylsulfinylphenyl)-1H-imidazo[4,5-b]pyridine
    CAS Number
    PubChem CID
    UNII
    CompTox Dashboard (EPA)
    ECHA InfoCard 100.070.348
    Chemical and physical data
    Formula C14H13N3O2S
    Molar mass 287.34 g·mol−1
    3D model (JSmol)
    • COC1=C(C=CC(=C1)S(=O)C)C2=NC3=C(N2)C=CC=N3

    Sulmazole is a cardiotonic drug. Sulmazole has the chemical formula C14H13N3O2S and a molecular weight of 287.34 g/mol.

    Sulmazole has been shown to improve cardiac index and reduce pulmonary capillary wedge pressure without significant changes in a person's heart rate or arterial pressure. Sulmazole inhibits the A1 adenosine receptor and functionally blocks Gi, an inhibitory regulator. Sulmazole is also a phosphodiesterase inhibitor. Sulmazole is classified as an imidazopyridine and a sulfoxide. Sulmazole can be taken intravenously or orally. Side effects from sulmazole include blurring vision and temporary color blindness.


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