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Mu-opioid receptor agonists
Tegileridine
Другие языки:

    Tegileridine

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    Tegileridine
    Tegileridine structure.png
    Identifiers
    • (1S,4S)-4-ethoxy-N-[2-[(9R)-9-pyridin-2-yl-6-oxaspiro[4.5]decan-9-yl]ethyl]-1,2,3,4-tetrahydronaphthalen-1-amine
    CAS Number
    PubChem CID
    Chemical and physical data
    Formula C28H38N2O2
    Molar mass 434.624 g·mol−1
    3D model (JSmol)
    • CCO[C@H]1CC[C@@H](C2=CC=CC=C12)NCC[C@]3(CCOC4(C3)CCCC4)C5=CC=CC=N5
    • InChI=1S/C28H38N2O2/c1-2-31-25-13-12-24(22-9-3-4-10-23(22)25)29-19-16-27(26-11-5-8-18-30-26)17-20-32-28(21-27)14-6-7-15-28/h3-5,8-11,18,24-25,29H,2,6-7,12-17,19-21H2,1H3/t24-,25-,27+/m0/s1
    • Key:YUMLNLMFBWBKSK-OHSXHVKISA-N

    Tegileridine is a drug which acts as a μ-opioid receptor agonist. It is closely related to compounds such as oliceridine, TRV734 and SHR9352, and shares a similar profile as a biased agonist selective for activation of the G-protein signalling pathway over β-arrestin 2 recruitment.

    See also


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