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Prodrug
Temocapril
Другие языки:

Temocapril

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Temocapril
Temocapril.svg
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
  • 2-[(2S)-6-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C23H28N2O5S2
Molar mass 476.61 g·mol−1
3D model (JSmol)
  • CCOC(=O)[C@H](CCc1ccccc1)NC2CS[C@@H](CN(C2=O)CC(=O)O)c3cccs3
  • InChI=1S/C23H28N2O5S2/c1-2-30-23(29)17(11-10-16-7-4-3-5-8-16)24-18-15-32-20(19-9-6-12-31-19)13-25(22(18)28)14-21(26)27/h3-9,12,17-18,20,24H,2,10-11,13-15H2,1H3,(H,26,27)/t17-,18?,20-/m0/s1
  • Key:FIQOFIRCTOWDOW-DXCJPMOASA-N
  (verify)

Temocapril (also known as temocaprilum [Latin]; brand name Acecol) is an ACE inhibitor. It was not approved for use in the US.

It is administered as inactive prodrug, then converted to its active metabolite, temocaprilat.

It was patented in 1984 and approved for medical use in 1994.



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