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Male contraceptive
Triptonide
Другие языки:

    Triptonide

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    Not to be confused with Triptolide, another derivative of Tripterygium wilfordii.
    Triptonide
    Triptonide.png
    Names
    IUPAC name
    (1S,2S,4S,5S,7S,9S,11S,13S)-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-ene-8,17-dione
    Other names
    Triptonide; NSC 165677; 14-deoxy-14-oxo-triptolide
    Identifiers
    3D model (JSmol)
    ChEBI
    ChEMBL
    ChemSpider
    PubChem CID
    • InChI=1S/C20H22O6/c1-8(2)18-13(25-18)14-20(26-14)17(3)5-4-9-10(7-23-15(9)21)11(17)6-12-19(20,24-12)16(18)22/h8,11-14H,4-7H2,1-3H3/t11-,12-,13-,14-,17-,18-,19+,20+/m0/s1
      Key: SWOVVKGLGOOUKI-ZHGGVEMFSA-N
    • CC(C)[C@@]12[C@@H](O1)[C@H]3[C@@]4(O3)[C@]5(CCC6=C([C@@H]5C[C@H]7[C@]4(C2=O)O7)COC6=O)C
    Properties
    C20H22O6
    Molar mass 358.390 g·mol−1
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    Triptonide is a chemical compound found in Tripterygium wilfordii, a plant used in traditional Chinese medicine. A 2021 trial in mice and monkeys suggested that triptonide may offer a reversible male contraceptive.


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