AB-PINACA

AB-PINACA

Legal status
Legal status	CA: Schedule II DE: Anlage II (Authorized trade only, not prescriptible) UK: Class B US: Schedule I
Identifiers
IUPAC name N-[(1S)-1-(Aminocarbonyl)-2-methylpropyl]-1-pentyl-1H-indazole-3-carboxamide
CAS Number	1445752-09-9 Y
PubChem CID	71301472
ChemSpider	28537615
UNII	6J3KC3S2PA
CompTox Dashboard (EPA)	DTXSID00904034
Chemical and physical data
Formula	C18H26N4O2
Molar mass	330.432 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCCCn1c2ccccc2c(n1)C(=O)N[C@@H](C(C)C)C(=O)N
InChI InChI=1S/C18H26N4O2/c1-4-5-8-11-22-14-10-7-6-9-13(14)16(21-22)18(24)20-15(12(2)3)17(19)23/h6-7,9-10,12,15H,4-5,8,11H2,1-3H3,(H2,19,23)(H,20,24)/t15-/m0/s1 Key:GIMHPAQOAAZSHS-HNNXBMFYSA-N

AB-PINACA is a compound that was first identified as a component of synthetic cannabis products in Japan in 2012.

It was originally developed by Pfizer in 2009 as an analgesic medication.

AB-PINACA acts as a potent agonist for the CB₁ receptor (K_i = 2.87 nM, EC₅₀ = 1.2 nM) and CB₂ receptor (K_i = 0.88 nM, EC₅₀ = 2.5 nM) and fully substitutes for Δ⁹-THC in rat discrimination studies, while being 1.5x more potent.

There have been a number of reported cases of deaths and hospitalizations in relation to this synthetic cannabinoid.

Legal status

Germany

AB-PINACA is an Anlage II controlled substance in Germany as of November 2014.

Singapore

It is listed in the Fifth Schedule of the Misuse of Drugs Act and so is illegal in Singapore, as of May 2015.

United States

It is a Schedule I controlled substance in the United States.

China

It is a controlled substance in China as of October 2015.

France

It is a controlled substance in France as of March 2017.

See also