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Respiratory system drug stubs
Acefylline
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Acefylline

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Acefylline
Skeletal formula of acefylline
Ball-and-stick model of the acefylline molecule
Clinical data
ATC code
Identifiers
  • (1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.010.447
Chemical and physical data
Formula C9H10N4O4
Molar mass 238.203 g·mol−1
3D model (JSmol)
  • O=C2N(c1ncn(c1C(=O)N2C)CC(=O)O)C
  • InChI=1S/C9H10N4O4/c1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h4H,3H2,1-2H3,(H,14,15) checkY
  • Key:HCYFGRCYSCXKNQ-UHFFFAOYSA-N checkY
  (verify)

Acefylline (INN), also known as acetyloxytheophylline, is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation etanautine to help offset diphenhydramine induced drowsiness.

A silanol–mannuronic acid conjugate of acefylline, acefylline methylsilanol mannuronate (INCI; trade name Xantalgosil C) is marketed as a lipolytic phosphodiesterase inhibitor. It is used as an ingredient in cosmeceuticals for the treatment of cellulite and as a skin conditioner.

See also


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