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Aceglutamide
Другие языки:
Aceglutamide
Подписчиков: 0, рейтинг: 0
Names | |
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Preferred IUPAC name
2-Acetamido-5-amino-5-oxopentanoic acid | |
Other names
2-(Acetylamino)-glutaramidic acid
α-N-Acetylglutamine; | |
Identifiers | |
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3D model (JSmol)
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ChemSpider | |
DrugBank |
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ECHA InfoCard | 100.017.862 |
EC Number |
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KEGG |
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MeSH | aceglutamide |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C7H12N2O4 | |
Molar mass | 188.183 g·mol−1 |
Appearance | White crystals |
Melting point | 197 °C (387 °F; 470 K) |
Related compounds | |
Related alkanoic acids
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Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Aceglutamide (brand name Neuramina), or aceglutamide aluminium (brand name Glumal), also known as acetylglutamine, is a psychostimulant, nootropic, and antiulcer agent that is marketed in Spain and Japan. It is an acetylated form of the amino acid L-glutamine, the precursor of glutamate in the body and brain. Aceglutamide functions as a prodrug to glutamine with improved potency and stability.
Aceglutamide is used as a psychostimulant and nootropic, while aceglutamide aluminium is used in the treatment of ulcers. Aceglutamide can also be used as a liquid-stable source of glutamine to prevent damage from protein energy malnutrition. The drug has shown neuroprotective effects in an animal model of cerebral ischemia.
See also
H2 antagonists ("-tidine") | |
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Prostaglandins (E)/ analogues ("-prost-") |
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Proton-pump inhibitors ("-prazole") |
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Potassium-competitive acid blockers ("-prazan") |
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Others | |
Combinations | |
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Magnesium (increases motility) | |
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Aluminium (decreases motility) | |
Calcium | |
Sodium | |
Combinations and complexes of aluminium, calcium and magnesium |