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Allopurinol hypersensitivity syndrome
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    Allopurinol hypersensitivity syndrome

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    Allopurinol hypersensitivity syndrome
    Allopurinol structure.png
    Allopurinol
    Symptoms Fever, Cutaneous Reaction, Eosinophilia, Acute Renal Failure
    Treatment Systematic Corticosteroids
    Frequency Rare

    Allopurinol hypersensitivity syndrome typically occurs in persons with preexisting kidney failure. Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal necrolysis.

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