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Amenamevir
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Amenamevir

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Amenamevir
Amenamevir.svg
Clinical data
Trade names Amenalief
Other names ASP-2151, ASP2151
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • N-(2,6-Dimethylphenyl)-N-[2-[4-(1,2,4-oxadiazol-3-yl)anilino]-2-oxoethyl]-1,1-dioxothiane-4-carboxamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
Chemical and physical data
Formula C24H26N4O5S
Molar mass 482.56 g·mol−1
3D model (JSmol)
  • Cc1cccc(C)c1N(CC(=O)Nc1ccc(-c2ncon2)cc1)C(=O)C1CCS(=O)(=O)CC1
  • InChI=1S/C24H26N4O5S/c1-16-4-3-5-17(2)22(16)28(24(30)19-10-12-34(31,32)13-11-19)14-21(29)26-20-8-6-18(7-9-20)23-25-15-33-27-23/h3-9,15,19H,10-14H2,1-2H3,(H,26,29)
  • Key:MNHNIVNAFBSLLX-UHFFFAOYSA-N

Amenamevir (trade name Amenalief) is an antiviral drug used for the treatment of shingles (herpes zoster).

It acts as an inhibitor of the zoster virus's helicase–primase complex. Amenamevir was approved in Japan for the treatment of shingles in 2017.



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