Ataxia-telangiectasia group D complementing

Ataxia-telangiectasia group D complementing (ATDC) is a gene implicated in ataxia-telangiectasia.

It is involved in a mouse model of pancreatic cancer.

Further reading

• Brzoska PM, Chen H, Zhu Y, Levin NA, Disatnik MH, Mochly-Rosen D, Murnane JP, Christman MF (1995). "The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor". Proc. Natl. Acad. Sci. U.S.A. 92 (17): 7824–8. Bibcode:1995PNAS...92.7824B. doi:10.1073/pnas.92.17.7824. PMC 41238. PMID 7644499.
• Murnane JP, Zhu Y, Young BR, Christman MF (1994). "Expression of the candidate A-T gene ATDC is not detectable in a human cell line with a normal response to ionizing radiation". Int. J. Radiat. Biol. 66 (6 Suppl): S77-84. doi:10.1080/09553009414551901. PMID 7836856.
• Laderoute KR, Knapp AM, Green CJ, Sutherland RM, Kapp LN (1996). "Expression of the ATDC (ataxia telangiectasia group D-complementing) gene in A431 human squamous carcinoma cells". Int. J. Cancer. 66 (6): 772–8. doi:10.1002/(SICI)1097-0215(19960611)66:6<772::AID-IJC11>3.0.CO;2-5. PMID 8647648. S2CID 29088136.
• Hosoi Y, Kapp LN, Murnane JP, Matsumoto Y, Enomoto A, Ono T, Miyagawa K (2006). "Suppression of anchorage-independent growth by expression of the ataxia-telangiectasia group D complementing gene, ATDC". Biochem. Biophys. Res. Commun. 348 (2): 728–34. doi:10.1016/j.bbrc.2006.07.115. PMID 16890201.
• Tauchi H, Green C, Knapp M, Laderoute K, Kapp L (2000). "Altered splicing of the ATDC message in ataxia telangiectasia group D cells results in the absence of a functional protein". Mutagenesis. 15 (2): 105–8. doi:10.1093/mutage/15.2.105. PMID 10719033.