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Antifungal drug
Aureoverticillactam
Другие языки:

    Aureoverticillactam

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    Aureoverticillactam
    Aureoverticillactam.png
    Names
    IUPAC name
    (3E,5E,7E,13Z,15E,17E,19E)-22-[(E)-Hex-2-enyl]-9,10,12-trihydroxy-17-methyl-1-azacyclodocosa-3,5,7,13,15,17,19-heptaen-2-one
    Identifiers
    3D model (JSmol)
    ChEMBL
    ChemSpider
    PubChem CID
    • InChI=1S/C28H39NO4/c1-3-4-5-8-17-24-18-13-11-15-23(2)16-12-14-19-25(30)22-27(32)26(31)20-9-6-7-10-21-28(33)29-24/h5-16,19-21,24-27,30-32H,3-4,17-18,22H2,1-2H3,(H,29,33)/b7-6+,8-5+,13-11+,16-12+,19-14-,20-9+,21-10+,23-15+
      Key: VMKRIAILWBEBLR-TWCCLTHVSA-N
    • CCC/C=C/CC1C/C=C/C=C(/C=C/C=C\C(CC(C(/C=C/C=C/C=C/C(=O)N1)O)O)O)\C
    Properties
    C28H39NO4
    Molar mass 453.623 g·mol−1
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    Aureoverticillactam is an antifungal macrocyclic lactam with the molecular formula C28H39NO4 which is produced by the marine bacterium Streptomyces aureoverticillatus. Aureoverticillactam has also cytotoxic activity.

    Further reading

    • Kim, Se-Kwon (27 November 2014). Handbook of Anticancer Drugs from Marine Origin. Springer. p. 245. ISBN 978-3-319-07145-9.
    • Patra, Jayanta Kumar; Shukla, Amritesh C.; Das, Gitishree (30 March 2020). Advances in Pharmaceutical Biotechnology: Recent Progress and Future Applications. Springer Nature. p. 343. ISBN 978-981-15-2195-9.

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