Benexate

Benexate

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name Phenylmethyl 2-[4-[(diaminomethylideneamino)methyl]cyclohexanecarbonyl]oxybenzoate
CAS Number	78718-52-2
PubChem CID	2316
ChemSpider	2226 Y
UNII	O3PR2X907M
ChEMBL	ChEMBLCHEMBL2104696
Chemical and physical data
Formula	C23H27N3O4
Molar mass	409.486 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(OCc1ccccc1)c3ccccc3OC(=O)C2CCC(C/N=C(\N)N)CC2
InChI InChI=1S/C23H27N3O4/c24-23(25)26-14-16-10-12-18(13-11-16)21(27)30-20-9-5-4-8-19(20)22(28)29-15-17-6-2-1-3-7-17/h1-9,16,18H,10-15H2,(H4,24,25,26) Y Key:IAXUQWSLRKIRFR-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Benexate (BEX) is an anti-ulcer agent used in the treatment of acid-related disorders. It is unique in its inability to form salts that are both non-bitter and soluble.

Medical uses

Benexate is approved from treatment of gastric ulcer in Japan.

Mechanism of action

The mechanism of action of benexate involves promotion of prostaglandin synthesis, protein secretion, and blood flow stimulation in the gastrointestinal tract.

See also

• Famotidine
• Powder diffraction
• Sugar substitute
• Crystal engineering

Further reading

• Rui Tamura, Mikiji Miyata, ed. (2015). Advances in Organic Crystal Chemistry: Comprehensive Reviews 2015 (1st ed.). Springer Japan. doi:10.1007/978-4-431-55555-1. ISBN 978-4-431-55554-4. S2CID 93141904.