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Blosozumab
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Monoclonal antibody | |
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Type | Whole antibody |
Source | Humanized (from mouse) |
Target | SOST |
Clinical data | |
ATC code |
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Identifiers | |
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ChemSpider |
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UNII | |
KEGG |
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Chemical and physical data | |
Formula | C6462H9852N1684O2030S46 |
Molar mass | 145086.42 g·mol−1 |
NY (what is this?) (verify) |
Blosozumab binds SOST, a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density. Blosozaumab has been studied with regards to the treatment of osteoporosis in both men and postmenopausal women. Clinical trials with Blosozumab have shown the antibody to be well tolerated and effective in producing a bone anabolic effect.
Blosozumab was developed by Eli Lilly and Company.
Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems
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Bone |
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Musculoskeletal |
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Circulatory |
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Neurologic |
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Angiogenesis inhibitor |
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Growth factor |
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