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Blosozumab
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Blosozumab

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Blosozumab
Monoclonal antibody
Type Whole antibody
Source Humanized (from mouse)
Target SOST
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
Formula C6462H9852N1684O2030S46
Molar mass 145086.42 g·mol−1
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Blosozumab binds SOST, a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density. Blosozaumab has been studied with regards to the treatment of osteoporosis in both men and postmenopausal women. Clinical trials with Blosozumab have shown the antibody to be well tolerated and effective in producing a bone anabolic effect.

Blosozumab was developed by Eli Lilly and Company.


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