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Carbarsone
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Carbarsone

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Carbarsone
Carbarsone.png
Names
Preferred IUPAC name
[4-(Carbamoylamino)phenyl]arsonic acid
Other names
(4-Ureidophenyl)arsonic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.004.077
EC Number
  • 204-484-6
MeSH Carbarson
PubChem CID
UNII
  • InChI=1S/C7H9AsN2O4/c9-7(11)10-6-3-1-5(2-4-6)8(12,13)14/h1-4H,(H3,9,10,11)(H2,12,13,14) checkY
    Key: WWXBHTZSYYGCSG-UHFFFAOYSA-N checkY
  • InChI=1/C7H9AsN2O4/c9-7(11)10-6-3-1-5(2-4-6)8(12,13)14/h1-4H,(H3,9,10,11)(H2,12,13,14)
    Key: WWXBHTZSYYGCSG-UHFFFAOYAW
  • O=C(Nc1ccc(cc1)[As](=O)(O)O)N
  • NC(=O)NC1=CC=C(C=C1)[As](O)(O)=O
Properties
C7H9AsN2O4
Molar mass 260.081 g·mol−1
Pharmacology
Oral
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Carbarsone is an organoarsenic compound used as an antiprotozoal drug for treatment of amebiasis and other infections. It was available for amebiasis in the United States as late as 1991. Thereafter, it remained available as a turkey feed additive for increasing weight gain and controlling histomoniasis (blackhead disease).

Carbarsone is one of four arsenical animal drugs approved by the U.S. Food and Drug Administration for use in poultry and/or swine, along with nitarsone, arsanilic acid, and roxarsone. In September 2013, the FDA announced that Zoetis and Fleming Laboratories would voluntarily withdraw current roxarsone, arsanilic acid, and carbarsone approvals, leaving only nitarsone approvals in place. In 2015 FDA withdrew the approval of using nitarsone in animal feeds. The ban came into effect at the end of 2015.


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