CCG-4986

CCG-4986

Identifiers
IUPAC name methyl-N-[(4-chlorophenyl)sulfonyl]-4-nitrobenzenesulfinimidoate
CAS Number	7134-19-2 Y
PubChem CID	1328227
ChemSpider	1113062
UNII	TJ1W0H78EJ
ECHA InfoCard	100.161.330
Chemical and physical data
Formula	C13H11ClN2O5S2
Molar mass	374.81 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=[N](=O)c1ccc(cc1)\S(\OC)=N\S(=O)(=O)c(cc2)ccc2Cl
InChI InChI=1S/C13H11ClN2O5S2/c1-21-22(12-6-4-11(5-7-12)16(17)18)15-23(19,20)13-8-2-10(14)3-9-13/h2-9H,1H3 Key:GIFNUYPIOIDEGE-UHFFFAOYSA-N
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CCG-4986 is a drug which is the first non-peptide compound discovered that acts as a selective inhibitor of the regulator of G protein signalling protein subtype RGS4. Regulators of G protein signalling are proteins which act to limit and shorten the response produced inside a cell following activation of a G protein-coupled receptor. Since different RGS subtypes are expressed in different tissues and are associated with particular receptors, this makes it possible for selective inhibitors of RGS proteins to be developed, which should be able to enhance the activity of a particular receptor in a defined target tissue, but not elsewhere in the body.