Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.

Cefmenoxime

Подписчиков: 0, рейтинг: 0
Cefmenoxime
Cefmenoxime.svg
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Intramuscular, intravenous
ATC code
Pharmacokinetic data
Bioavailability 100% (given IM)
Protein binding 50% to 70%
Metabolism Negligible
Elimination half-life 1 hour
Excretion Kidney, unchanged
Identifiers
  • (6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-
    2-methoxyimino-acetyl]amino}-3-[(1-methyltetrazol-
    5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]
    oct-2-ene-2-carboxylic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C16H17N9O5S3
Molar mass 511.55 g·mol−1
3D model (JSmol)
  • O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sc3)N)CSc4nnnn4C)C(=O)O
  • InChI=1S/C16H17N9O5S3/c1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7/h5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29)/b21-8-/t9-,13-/m1/s1 checkY
  • Key:HJJDBAOLQAWBMH-YCRCPZNHSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Cefmenoxime is a third-generation cephalosporin antibiotic.

External links

  • Diseases Database (DDB): 30892
  • Yokota N, Koguchi M, Suzuki Y, Fukayama S, Ishihara R, Deguchi K, Oda S, Tanaka S, Nakane Y, Fukumoto T (1995). "Antibacterial activities of cefmenoxime against recent fresh clinical isolates from patients in sinusitis". Jpn J Antibiot. 48 (5): 602–9. PMID 7637194.
  • Paladino J, Fell R (1994). "Pharmacoeconomic analysis of cefmenoxime dual individualization in the treatment of nosocomial pneumonia". Ann Pharmacother. 28 (3): 384–9. doi:10.1177/106002809402800316. PMID 8193431. S2CID 29444681.
  • Duncker G, Reich U, Krausse R (1994). "Cefmenoxime in corneal organ culture". Ophthalmologica. 208 (5): 262–6. doi:10.1159/000310505. PMID 7816419.



Новое сообщение